Mast Cell Matters Podcast

Welcome to the Mast Cell Matters Podcast with Dr. Tania Dempsey. Each episode is a deep dive on Mast Cell Activation Syndrome (MCAS) with a top physician, researcher or other expert who specializes in treating patients with MCAS.

In the show, we take a practical approach to helping doctors and patients better manage MCAS. We cover the symptoms, testing, diagnosis, treatment, challenges, practical strategies, common comorbidities (e.g., POTS, hypermobility spectrum disorders, ME/CFS, autoimmunity, GI dysmotility), latest research findings and clinical pearls.

These episodes are a monthly feature of The POTScast, presented by Standing Up to POTS, a non-profit dedicated to improving life for those with POTS and related chronic illness. Check out our full podcast — with other types of great episodes — at

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Cardiac manifestations of MCAS with Dr. Andrew Maxwell

Treating MCAS, POTS, and Long COVID can be difficult, and physicians must attack from various angles to get patients…

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GI Manifestations of MCAS with Dr. Leonard Weinstock

Dr. Weinstock, a gastroenterologist and leading expert on MCAS, discusses mast cells in the context of the GI tract.…

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Dr. Lawrence Afrin on MCAS Diagnostic Criteria “Consensus-2”

Dr. Afrin, a world expert in all things mast cell, talks in depth about issues with the first MCAS "consensus"…

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Diagnosis & Treatment of MCAS with Dr. Tania Dempsey

Dr. Dempsey shares her experience in both diagnosing and treating people with MCAS. She always looks for POTS and…

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Introduction to mast cells and mast cell activation syndrome (MCAS) with Dr. Tania Dempsey

Dr. Dempsey is helping us to launch a new series within the POTScast focusing on all things mast cells. These cells are…